GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs703842 | 1 | rs11172343 | chr12:58188157 | TSFM | chr12:58176536-58191367:+ | -0.36 | -10.51 | 1.19E-24 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172343 | chr12:58188157 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.19 | -5.1 | 3.94E-7 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | B4GALNT1 | chr12:58019551-58026985:- | 0.12 | 3.63 | 0.000293 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | FAM119B | chr12:58166383-58176323:+ | 0.43 | 11.04 | 6.59E-27 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | TSFM | chr12:58176536-58191367:+ | -0.34 | -10.35 | 5.57E-24 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172344 | chr12:58193448 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.17 | -4.96 | 8.29E-7 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172349 | chr12:58212528 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 10.14 | 3.77E-23 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172349 | chr12:58212528 | TSFM | chr12:58176536-58191367:+ | -0.35 | -10.31 | 7.72E-24 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs11172349 | chr12:58212528 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.19 | -5.28 | 1.55E-7 | Multiple sclerosis |
| BRCA | cis | rs2404602 | 1 | rs1117367 | chr15:76872330 | SCAPER | chr15:76640529-77197744:- | -0.18 | -6.41 | 2.22E-10 | Blood metabolite levels |
| BRCA | cis | rs11174436 | 1 | rs11174399 | chr12:62646556 | FAM19A2 | chr12:62102043-62653925:- | 0.16 | 3.62 | 0.000312 | Pyoderma gangrenosum in inflammatory bowel disease |
| BRCA | cis | rs11174436 | 1 | rs11174409 | chr12:62669178 | FAM19A2 | chr12:62102043-62653925:- | 0.17 | 3.79 | 0.000158 | Pyoderma gangrenosum in inflammatory bowel disease |
| BRCA | cis | rs11174436 | 1 | rs11174410 | chr12:62671564 | FAM19A2 | chr12:62102043-62653925:- | 0.17 | 3.78 | 0.000168 | Pyoderma gangrenosum in inflammatory bowel disease |
| BRCA | cis | rs11174436 | 1 | rs11174436 | chr12:62743348 | FAM19A2 | chr12:62102043-62653925:- | 0.18 | 3.88 | 0.000113 | Pyoderma gangrenosum in inflammatory bowel disease |
| BRCA | cis | rs11174436 | 1 | rs11174437 | chr12:62744626 | FAM19A2 | chr12:62102043-62653925:- | 0.18 | 3.88 | 0.000113 | Pyoderma gangrenosum in inflammatory bowel disease |